Potential risk factors for mild cognitive impairment in the elderly population in communities of Shanghai
10.3969/j.issn.1006-2483.2020.02.031
- VernacularTitle:上海市社区老年人轻度认知障碍的潜在危险因素
- Author:
Yuqing TANG
1
;
Jingyu TAN
1
;
Xin HU
1
;
Guangcheng HUANG
1
;
Jiaye GONG
2
;
Qing XU
2
;
Huiyong CAI
2
;
Yulan QIU
1
;
Nannan FENG
1
Author Information
1. School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
2. Dapuqiao Street Community Health Service Center, Huangpu District, Shanghai 200023, China
- Publication Type:Journal Article
- Keywords:
Mild cognitive impairment;
Risk factors;
Community;
Elderly population
- From:
Journal of Public Health and Preventive Medicine
2020;31(2):126-130
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the potential risk factors for mild cognitive impairment (MCI) in the elderly population in the community, and to provide a basis for the primary prevention of MCI. Methods A cross-sectional study of elderly population in communities of Shanghai, China was conducted. A total of 368 subjects including both males and females, aged 65-80 years old, were selected to complete the mini-mental state examination (MMSE), basic information questionnaires, and physical examinations. Logistic regression analysis was used to analyze the potential risk factors of MCI. Results Of the 368 subjects participating in the study, 53 were found to have MCI and the prevalence rate was 14.4%. Univariate analysis found that older age, low education, no folic acid supplementation, stroke, osteoporosis and hyperlipidemia were risk factors of MCI. Multiple logistic regression analysis showed that advanced age [OR=1.146 (95%CI: 1.052-1.249)] and osteoporosis [OR=2.371 (95%CI: 1.042-5.396)] were the independent risk factors for MCI, while higher education [OR=0.073 (95%CI: 0.011-0.478)] was a protective factor. Age influenced all the aspects of MMSE scores (all P values <0.05). In addition, the analysis of the results suggested that subjects with regular folic acid supplementation got higher MMSE scores, especially in the aspect of language and praxis (P=0.002). On the contrary, patients with osteoporosis had lower attention and computing power scores (P=0.022). Conclusion The prevalence of MCI increased with age. Low education and osteoporosis may be the independent risk factors for MCI in the elderly population. Although no association was observed between folic acid supplementation and MCI, folic acid supplementation could improve the performance of language and praxis.
