Investigation on colonization status of Streptococcus pneumoniae and Haemophilus influenzae in healthy infants in Wuhan
10.3969/j.issn.1006-2483.2020.02.018
- VernacularTitle:武汉市健康婴儿鼻咽部肺炎链球菌及流感嗜血杆菌定植状况的调查
- Author:
Defeng ZHAO
1
;
Fang WANG
1
;
Jian CHEN
1
;
Li CAI
1
;
Li WEN
1
;
Yan XIONG
1
Author Information
1. Wuhan Centers for Disesae Control and Prevention, Wuhan 430015, China
- Publication Type:Journal Article
- Keywords:
Healthy infants;
Streptococcus pneumonia;
Haemophilus influenza;
Colonization;
Carrying rate
- From:
Journal of Public Health and Preventive Medicine
2020;31(2):74-77
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the colonization status of Streptococcus pneumoniae and Haemophilus influenzae in nasopharynx of healthy infants in Wuhan. Methods Six vaccination clinics were randomly selected, and the nasopharyngeal specimens of healthy infants were collected and cultured for Streptococcus pneumoniae and Haemophilus influenza. Results The carrying rate of Streptococcus pneumoniae and Haemophilus influenzae in 998 healthy infants was 18.84% and 17.54%, respectively. The carrying rate of Streptococcus pneumoniae and Haemophilus influenzae within 6 months of age was 15.79% and 14.39%, and the carrying rate of Streptococcus pneumoniae and Haemophilus influenzae at 7-12 months old was 22.90% and 21.73%, respectively. The difference was statistically significant (Sp: χ2=5.60 P=0.02; Hi：χ2=8.98 P=0.00); The carrying rate of Streptococcus pneumoniae in urban and suburban areas was 18.08% and 19.78%, respectively, and the Haemophilus influenzae carrying rate was 17.18% and 17.98%, respectively. The differences were not statistically significant (Sp：χ2=0.47 P=0.50; Hi：χ2=0.11 P=0.74). The correlation coefficient (r value) of the age of the month and the carrying rate of sp and hi was 0.98 and 0.96, respectively. Conclusion The age of healthy infants in Wuhan was highly linearly and positively correlated with the carrying rate of Streptococcus pneumoniae and Haemophilus influenza.
