Epidemiological investigation of a family clustering of COVID-19

Qun Guan; Miao Liu; Yingjie Zhuang; Yue Yuan; Shengshu Wang; Jin LI; Zhu Chen; Xinglong Yang; Zirong Tang; Hongjun Jia; Jingyi MA; Xiaoxia Wang; Penggang Tai; Jing LI; Yingjie Zhuang; Yao HE

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Epidemiological investigation of a family clustering of COVID-19

VernacularTitle: 一起新型冠状病毒肺炎家族聚集性疫情流行病学调查分析
Author: Qun GUAN ¹ ; Miao LIU ² ; Yingjie ZHUANG ¹ ; Yue YUAN ¹ ; Shengshu WANG ² ; Jin LI ¹ ; Zhu CHEN ¹ ; Xinglong YANG ¹ ; Zirong TANG ¹ ; Hongjun JIA ¹ ; Jingyi MA ¹ ; Xiaoxia WANG ¹ ; Penggang TAI ³ ; Jing LI ¹ ; Yingjie ZHUANG ¹ ; Yao HE ²
Author Information

1. The Fifth Medical Center of Chinese People’s Liberation Army General Hospital, Beijing 100039, China
2. Institute of Geriatrics, Second Medical Center, National Clinical Research Center for Geriatrics Diseases, Beijing Key Laboratory of Aging and Geriatrics, Chinese People’s Liberation Army General Hospital, Beijing 100853, China
3. Medical Service Department, Chinese People’s Liberation Army General Hospital, Beijing 100083, China
Publication Type:Journal Article
Keywords: COVID-19; Family clustering; Epidemiological investigation
From: Chinese Journal of Epidemiology 2020;41(5):629-633
CountryChina
Language:Chinese
Abstract: Objective To investigate the epidemiological characteristics of a family clustering of COVID-19. Methods Field epidemiological survey was conducted. Result Case 1 of the long-term residents from Hubei province was the source of infection of this family clustering. There were 6 cases (from case 2 to case 7) infected in the whole incubation period. The incubation period was more than 14 days for 3 of the second-generation cases. Routes of transmission include respiratory droplets (from case 1 transmitted to case 6, from case 1 to her family members) and closecontact (from case 1 to other cases in her family). All the age groups were generally susceptible, while elderly were easier to progress to critically ill. Besides respiratory symptoms, there were also gastrointestinal symptoms, of which diarrhea was the most common one. Conclusion Family clustering had been an important part for COVID-19 cases.