The application and perspectives of organoids in tumor research
10.3872/j.issn.1007-385x.2018.07.002
- VernacularTitle:类器官在肿瘤研究中的应用及展望
- Author:
XU Huawei
1
;
ZHAN Xianbao
1
Author Information
1. Department of Oncology, Changhai Hospital Affiliated to Second Military Medical University, Shanghai 200433,China
- Publication Type:Journal Article
- Keywords:
organoid;
tumormodel;
drugscreening;
individualizedmedicine;
translationalmedicine
- From:
Chinese Journal of Cancer Biotherapy
2018;25(7):669-673
- CountryChina
- Language:Chinese
-
Abstract:
Over the last few decades progress in the field of stem cell biology makes a new kind of 3-D human cells in vitro culture techniques available, which is termed organoids because of its space structure similar to organs. Organoids derived from tumor tissues largely retained the biological characteristics of tumor tissue in vivo, and both the advantages of low cost and easy operation make up the defects of the previous conventional cancer models. Organoids can also be used for translational medical research, formulating individual therapeutic schedules including drug sensitive tests, and combining with many kinds of technologies. This article focus on the application and prospectsoforganoidsintumorresearch.
- Full text:20180702.pdf
