Advanced research of immune-related response evaluation criteria in solid tumors
10.3872/j.issn.1007-385x.2018.07.001
- VernacularTitle:实体肿瘤免疫相关疗效评价标准的研究进展
- Author:
BAI Rilan
1
;
CUI Jiuwei
1
Author Information
1. Cancer Center, the First Hospital of Jilin University, Changchun 130021, Jilin, China
- Publication Type:Journal Article
- Keywords:
solid tumor;
tumor immunotherapy;
pseudoprogression;
response evaluation criteria
- From:
Chinese Journal of Cancer Biotherapy
2018;25(7):663-668
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, therapy of immune checkpoint inhibitors have developed rapidly and made breakthrough, becoming the first-line treatment for many types of advanced cancer. However, due to its particular mode in activating the anti-tumor immune system, a variety of unconventional response patterns have emerged, such as delayed response and pseudoprogression, which have challenged the traditional response evaluation criteria and encouraged people to continuously explore new criteria for evaluating the unconventional response patterns under immunotherapy. This article mainly reviews the process of exploration, advanced research,as well as similarities and differencesamongvarious immune-related efficacy evaluation criteria, and finally prospects the current challenges and future trends.
- Full text:20180701.pdf
