Research status and application progress of CRISPR/Cas9 delivery system
10.11665/j.issn.1000-5048.20200102
- VernacularTitle:CRISPR/Cas9递送系统的研究现状及应用进展
- Author:
Xiuhua PAN
1
;
Zhenghong WU
;
Xiaole QI
Author Information
1. 中国药科大学药学院药剂系
- Publication Type:Journal Article
- Keywords:
CRISPR/Cas9 system;
gene editing;
viral vector;
non-viral vector;
gene therapy
- From:
Journal of China Pharmaceutical University
2020;51(1):10-18
- CountryChina
- Language:Chinese
-
Abstract:
Based on the three delivery forms of CRISPR/Cas9 system at the levels of DNA, RNA and protein, this paper mainly approaches the development and new strategies of CRISPR/Cas9 delivery systems, as well as their application in the biomedical field and the clinical treatment of gene-related diseases. By summarizing and elaborating the CRISPR/Cas9 system delivery and gene therapy strategy, new ideas are provided for the discovery of innovative drugs and the development of gene therapy.
