Progress in genetic research on keratoconus
10.3980/j.issn.1672-5123.2020.5.11
- VernacularTitle:圆锥角膜的遗传学研究进展
- Author:
Li-Yan Xu
1
,
2
,
3
Author Information
1. Henan Provincial People'
2. s Hospital, Henan Eye Hospital, Henan Eye Institute, People'
3. s Hospital of Zhengzhou University, Zhengzhou 450003, Henan Province, China
- Publication Type:Review
- Keywords:
keratoconus;
genetics;
nuclear genome;
mitochondrial genome;
epigenetics
- From:
International Eye Science
2020;20(5):796-800
- CountryChina
- Language:Chinese
-
Abstract:
Keratoconus is a corneal disease characterized by corneal ectasia, progressive corneal thinning, conical protrusion and irregular astigmatism. Several studies have indicated that keratoconus is a complex disease with genetic heterogeneity. Genetic studies on keratoconus involving nuclear genome, mitochondrial genome and epigenetics were increasing. This article reviews the recent progress in genetic research on keratoconus.
- Full text:202005011.pdf
