Advances in research on the prevention and treatment of dental erosion b y MMPs inhibitors
- VernacularTitle:基质金属蛋白酶抑制剂防治牙酸蚀症的研究进展
- Author:
JIANG Nengwu
1
;
YU Hao
1
Author Information
- Publication Type:Review
- Keywords: Dental erosion; Dentin; Prevention; Therapy; MMPs; MMPs inhibitors
- From: Journal of Prevention and Treatment for Stomatological Diseases 2017;25(12):810-813
- CountryChina
- Language:Chinese
- Abstract: High prevalence of dental erosion has been reported in recent years. The prevention and treatment of dental erosion has therefore attracted lots of attention in dentistry. Matrix metalloproteinases (MMPs) is a type of proteolytic enzyme containing Zn2+ and Ca2+, which can degrade organic matrix in advanced dental erosion. MMPs inhibitors were reported to have the potential to prevent the organic matrix of dentin from degradation, which might provide protective capacity against dental erosion. The present article reviews the mechanism and potential application of MMPs inhibitors in the prevention and treatment of dental erosion.
- Full text:基质金属蛋白酶抑制剂防治牙酸蚀症的研究进展.pdf
