Detection of sTREM-1 levels in gingival crevicular fluid of peri-implantitis
10.12016/j.issn.2096-1456.2017.12.007
- Author:
ZHENG Dechun
1
;
WU Dong
2
Author Information
1. Department of Stomatology The Affiliated Hospital of Putian University
2. Department of Implantology Stomatological Hospital Fujian Medical University
- Publication Type:Journal Article
- Keywords:
Peri-implantitis;
Gingival crevicular fluid;
sTREM-1;
mSBI;
PPD
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2017;25(12):784-787
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To investigate the relationship between the level of the soluble triggering receptor expressed on myeloid cell (sTREM-1) in the gingival crevicular fluid (GCF) of individuals and peri-implantitis.
Methods:46 patients (75 implants) with different severities of peri-implantitis and 18 patients (75 implants) without peri-implantitis were selected in this study. The concentrations of sTREM-1 in GCF with different types of peri-implantitis were detected by enzyme-linked immunosorbent assay (ELISA). The peri-implantitis peroxidase depth (PPD), the distance from the shoulder of the implant to the bottom of the bony defect (DSB), the modified sulcus bleeding index (mSBI) and the modified plaque index (mPLI) were recorded. The correlation between PPD, DSB, mSBI, mPLI and sTREM-1 was analyzed.
Results :The concentrations of sTREM-1 in GCF in mild, moderate and severe peri-implantitis group were significantly higher than those in healthy group (P < 0.05). The concentrations of sTREM-1 in GCF in severe peri-implantitis group were significantly higher than those in mild and moderate group (P < 0.05). There was no significant difference in the concentration of sTREM-1 in GCF between mild peri-implantitis group and moderate group (P > 0.05). In addition, there was a significant positive correlation between the concentration of sTREM-1 and PPD, DSB, mSBI, mPLI.
Conclusions :The concentration of sTREM-1 in GCF is closely related to the severity of tissue inflammation around implant.
- Full text:种植体周围炎龈沟液中sTREM-1水平的检测.pdf
