Metachronous Adenoid Cystic Carcinoma in the Peripheral Lung and at Base of the Tongue.

Author: Jun Hyun KIM ¹ ; Su Hyun AHN ; Jeong Min KIM ; So Yoon LEE
Author Information

1. Department of Otorhinolaryngology-Head and Neck Surgery, The Catholic University of Korea College of Medicine, Seoul, Korea.
Publication Type:Case Report
Keywords: Adenoid cystic carcinoma; Metachronous; Second primary neoplasms; Lung neoplasms
MeSH: Carcinoma, Adenoid Cystic*; Head; Lung Neoplasms; Lung*; Neck; Neoplasm Metastasis; Neoplasms, Second Primary; Recurrence; Thyroid Gland; Tongue*
From:Clinical and Experimental Otorhinolaryngology 2014;7(3):232-235
CountryRepublic of Korea
Language:English
Abstract: Primary lung adenoid cystic carcinoma (ACC) is extremely rare and accounts for approximately 0.1%-0.2% of all lung cancers. ACC of the head and neck has generally been regarded as a slow-growing, low-grade malignancy which has a tendency for local recurrence and frequent distant metastasis. When ACC of the lung is identified, physicians must determine whether it represents distant metastasis or a primary lung cancer. Thyroid transcription factor-1 staining is one of the most useful methods to differentiate primary from metastatic lesions in lung cancer. Herein we report a case of metachronous, not synchronous, ACC at the peripheral lung followed by ACC presentation at the base of the tongue, and review of relevant literatures.