A Case of p-ANCA-Positive Propylthiouracil-Induced Pyoderma Gangrenosum.
- Author:
Jong Won SEO
1
;
Hyun Ho SON
;
Joon Hee CHOI
;
Sook Kyung LEE
Author Information
- Publication Type:Case Report
- Keywords: p-ANCA; Propylthiouracil; Pyoderma gangrenosum
- MeSH: Antibodies, Antineutrophil Cytoplasmic; Graves Disease; Humans; Neutrophils; Propylthiouracil; Pyoderma; Pyoderma Gangrenosum; Skin Diseases; Vasculitis
- From:Annals of Dermatology 2010;22(1):48-50
- CountryRepublic of Korea
- Language:English
- Abstract: Propylthiouracil is a common medication used in patients with hyperthyroidism; it can cause perinuclear antineutrophil cytoplasmic antibodies (p-ANCA) in some patients with Graves' disease. This antibody has been associated with various forms of vasculitis and neutrophilic dermatosis. Herein, we report a patient who presented with cutaneous manifestations of pyoderma gangrenosum with simultaneous development of p-ANCAs during PTU therapy for Graves' disease.
