Diagnosis and treatment of primary biliary cholangitis-autoimmune hepatitis overlap syndrome
10.3969/j.issn.1001-5256.2020.03.051
- VernacularTitle:原发性胆汁性胆管炎-自身免疫性肝炎重叠综合征的诊治
- Author:
Ning YANG
1
;
Yansheng LIU
;
Ying HAN
Author Information
1. Department of Gastroenterology, Xijing Hospital, Air Force Medical University, Xi’an 710032, China
- Publication Type:Research Article
- Keywords:
primary biliary cholangitis;
hepatitis, autoimmune;
diagnosis;
therapeutics
- From:
Journal of Clinical Hepatology
2020;36(3):697-700
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune liver diseases (AILDs) include primary biliary cholangitis (PBC), autoimmune hepatitis (AIH), and primary sclerosing cholangitis. Some patients may have the features of two AILDs at initial diagnosis or during follow-up, which is usually referred to as “overlap syndrome”, among which PBC-AIH overlap is the most common type. Compared with those with PBC or AIH alone, the patients with PBC-AIH overlap syndrome tend to have higher incidence rates of portal hypertension, gastrointestinal bleeding, ascites, death, and liver transplantation, as well as more rapid disease progression, and therefore, early diagnosis and treatment is of great importance. This article reviews the recent advances in the diagnosis and treatment of PBC-AIH overlap syndrome.
