Mechanism of action of intestinal flora in hepatic encephalopathy
10.3969/j.issn.1001-5256.2020.03.049
- VernacularTitle:肠道菌群在肝性脑病中的作用机制
- Author:
Xiaotong JI
1
;
Yunhan HE
;
Yingyuan QI
Author Information
1. School of Medical technology, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, China
- Publication Type:Research Article
- Keywords:
hepatic encephalopathy;
microecology-gut-brain axis;
immune system;
flora transplantation
- From:
Journal of Clinical Hepatology
2020;36(3):690-692
- CountryChina
- Language:Chinese
-
Abstract:
Hepatic encephalopathy (HE) has various clinical symptoms, and its etiology and pathogenesis have not been fully understood. Recent studies have shown that the composition of intestinal flora is associated with the changes in the central nervous system in patients with HE. With reference to recent studies in China and foreign countries, this article analyzes and summarizes the regulatory mechanism of intestinal flora on HE through the liver-brain axis from the perspectives of microbiology, nervous system, and immunology, and it is pointed out that in-depth studies on the mechanism of action of intestinal flora are needed for the treatment of HE and can provide a clear basis for clinical diagnosis and treatment.
