Research advances in the role of macrophages in nonalcoholic fatty liver disease
10.3969/j.issn.1001-5256.2020.03.046
- VernacularTitle:巨噬细胞在非酒精性脂肪性肝病中的作用
- Author:
Yuxin LUO
1
;
Jinbo GUO
;
Xiaolan ZHANG
Author Information
1. Department of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
- Publication Type:Research Article
- Keywords:
non-alcoholic fatty liver disease;
macrophages;
therapeutics
- From:
Journal of Clinical Hepatology
2020;36(3):680-683
- CountryChina
- Language:Chinese
-
Abstract:
With the improvement of living standard, the incidence rate of nonalcoholic fatty liver disease (NAFLD) is gradually increasing year by year and its age of onset tends to become younger, but its pathogenesis remains unclear. Macrophages are important cells involved in the pathogenesis of NAFLD and have attracted great attention. This article elaborates on the origin and classification of liver macrophages, the role of macrophages in liver inflammation and related activation mechanism, and the drugs targeting macrophages, in order to provide a reference for the clinical treatment of NAFLD.
