Prevalence of gallstones among university teachers and related risk factors: A multicenter study
10.3969/j.issn.1001-5256.2020.03.031
- VernacularTitle:大学教师胆结石患病现状及危险因素的多中心研究
- Author:
Chi ZHANG
1
;
Shuling HU
;
Peng SUN
Author Information
1. National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Clinical Research Center for Cancer, Department of Prevention, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
- Publication Type:Research Article
- Keywords:
cholelithiasis;
risk factors;
college teachers;
multicenter studies as topic
- From:
Journal of Clinical Hepatology
2020;36(3):624-630
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the prevalence rate of gallstones among university teachers in Tianjin, China, and related risk factors. MethodsPhysical examination data were collected from the teachers from five universities who participated in physical examination in Physical Examination Center, Tianjin Medical University Cancer Institute and Hospital, in 2015, and abdominal ultrasound was used for the diagnosis of gallstones. The chi-square test was used for comparison of categorical data between groups. Univariate and multivariate logistic regression analyses were used to identify the risk factors for gallstones in the teachers from different universities, and a meta-analysis was used for the pooled analysis of prevalence rate and risk factors. ResultsA total of 8006 university teachers were enrolled, among whom 440 were diagnosed with gallstones, and the pooled prevalence rate of gallstones was 5.5%. The meta-analysis showed that hypertension (odds ratio ［OR］=1.67, 95% confidence interval ［CI］: 1.32-2.12, P＜0.001), fatty liver (OR=1.39, 95%CI: 1.12-1.72, P＜0.001), kidney stones (OR=1.90, 95%CI: 1.15-3.14, P=0.01), and high levels of hexokinase (OR=1.42, 95%CI: 1.03-1.94, P=0.03), alanine aminotransferase (OR=1.32, 95%CI: 1.01-1.73, P=0.04), and globulin (OR=1.74, 95%CI: 1.08-2.79, P=0.02) were risk factors for gallstones. ConclusionThere is a relatively low prevalence rate of gallstones among university teachers in Tianjin, and hypertension, fatty liver, kidney stones, and high levels of hexokinase, alanine aminotransferase, and globulin may be the risk factors for gallstones.
