Recent research advances in chronicity of drug-induced liver injury
10.3969/j.issn.1001-5256.2020.03.004
- VernacularTitle:药物性肝损伤慢性化的研究近况
- Author:
Ang HUANG
1
;
Ying SUN
;
Zhengsheng ZOU
Author Information
1. Treatment and Research Center for Non-infectious Liver Diseases, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China
- Publication Type:Research Article
- Keywords:
drug-induced liver injury;
chronic disease;
diagnosis;
therapeutics
- From:
Journal of Clinical Hepatology
2020;36(3):501-504
- CountryChina
- Language:Chinese
-
Abstract:
Although drug-induced liver injury (DILI) is often an acute process, about 20% of the patients may progress to chronic DILI. Chronic DILI has a long course of disease and there is still no effective treatment. With the development and clinical application of new drugs and the wide application of herbal and dietary supplements, the incidence rate of DILI chronicity gradually increases. This article overviews the latest research advances in DILI chronicity from the aspects of the epidemiology, risk factors, clinical manifestations, diagnosis, and treatment of DILI, so as to gain a comprehensive understanding of chronic DILI.