Clinical analysis of the predictive value of recurrent laryngeal nerve lymph nodes status for supraclavicular lymph node metastasis in esophageal squamous cell carcinoma
- VernacularTitle:食管癌喉返神经旁淋巴结预测锁骨上淋巴结转移的临床分析
- Author:
ZHENG Xiaodong
1
;
ZHANG Weimin
1
;
HOU Jianbin
1
Author Information
1. Department of Thoracic Surgery, Anyang Tumor Hospital, Anyang, 455000, Henan, P.R.China
- Publication Type:Journal Article
- Keywords:
Esophageal cancer;
three-field lymph node dissection;
recurrent laryngeal nerve lymph node;
supraclavicular lymph node
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2020;27(03):297-302
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the predictive value of recurrent laryngeal nerve lymph nodes (RLN) status for supraclavicular lymph node (SLN) metastasis in esophageal squamous cell carcinoma. Methods We retrospectively analyzed the clinical data of 83 patients with esophageal squamous cell carcinoma who underwent McKeown three-field lymphadenectomy from January 2017 to April 2018 in our hospital, including 53 males and 30 females with an average age of 64.07±7.05 years. Results The SLN metastasis rate of the patients was 24.1%. The rate in the thoracic and abdominal metastases positive (N1-3) group and negative (N0) group was 37.8% and 13.0%, respectively, with a statistical difference (P<0.05). The rate of SLN metastasis was significantly different between the RLN metastasis positive (RLN+) and negative (RLN–) groups (39.1% vs. 18.3%, P<0.05). One side of RLN metastasis could lead to SLN metastasis on the opposite side. No correlation between the SLN metastasis and age, gender, location, differentiation degree, maximum tumor diameter, T-staging or histologic type was observed (P>0.05). Multivariate analysis showed that lymph node metastasis in chest or abdomen was an independent predictor of SLN metastasis. Conclusion RLN+ is not the independent predictor for SLN metastasis. SLN should be dissected in N1-3 patients with esophageal squamous cell carcinoma without considering tumor location and T-staging. Bilateral SLN dissection should be recommended even if RLN metastasis is only unilateral.
