Prevalence and risk factors of Blastocystis hominis infection in inpatients in Jiangjin District, Chongqing City
10.16250/j.32.1374.2018244
- VernacularTitle:重庆市江津区社区医院住院人群人芽囊原虫感染情况及其影响因素分析
- Author:
Ji-Ming KANG
1
;
Yi-Ting LI
2
;
Rui CHEN
1
;
Ying-Fang YU
2
;
Xi-Tong LI
1
;
Xiu-Ping WU
2
;
Yan-Hong CHU
2
;
Jia-Xu CHEN
2
;
Shun-Xian ZHANG
2
;
Li-Guang TIAN
2
Author Information
1. Jiangjin District Center for Disease Control and Prevention, Chongqing 402260, China
2. National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory for Parasites and Vector Biology, National Health Commission, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, China
- Publication Type:Journal Article
- Keywords:
Blastocystis hominis;
Risk factor;
Genotype;
Community inpatient
- From:
Chinese Journal of Schistosomiasis Control
2019;31(5):479-485
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the prevalence and risk factors of Blastocystis hominis infection in inpatients in Jiangjin District, Chongqing City. Methods A cross-sectional study was conducted in a community hospital in Jiangjin District, Chongqing City, and the inpatients were surveyed by questionnaires. After obtaining the informed consent from the inpatients or legal guardians, the stool and blood samples were collected and examined by microscopy and PCR from April 17 to May 1, 2018. The univariate analysis and logistic regression analysis were used to analyze the risk factors of the B. hominis infection. Results A total of 198 hospitalized patients were investigated, and the infection rate of B. hominis was 10.61% (21/198), and the infection rate of the females (12.10%) was higher than that of the males (8.11%), but the difference was not statistically significant. The highest rate of infection was 19.23% in the age group of 10 to 20 years, followed by 17.74% in the age group of 60 years and above, and the lowest rate was 2.38% in the age group of 20 to 40 years. The difference in infection rates of B. hominis among the different age groups was statistically significant (P < 0.05). The infection rate of B. hominis in the people who used dry pail latrines was 33.30%, which was higher than that of the people who used water flush toilets (9.10%) (P < 0.05). The genotypes of B. hominis were ST1, ST3, ST6 and ST7, and ST6 and ST3 being the most predominant genotypes which accounted for 47.62% (10/21) and 38.10% (8/21) respectively, and among the infected males, the genotypes were only ST3 and ST6. The multiple logistic regression analysis showed that among the factors affecting B. hominis infection, only keeping pets was a risk factor [OR = 3.798, 95% CI (1.245, 11.581), P < 0.05]. Conclusion A high prevalence of B. hominis infection is found in the inpatients in Jiangjin District, Chongqing City, the predominant genotypes are ST6 and ST3, and keeping pets may be one of the main risk factors.
