Analysis of current drug treatment against clonorchiasis in China
10.16250/j.32.1374.2018113
- VernacularTitle:中国华支睾吸虫病药物治疗现状分析
- Author:
Men-bao QIAN
1
,
2
,
3
,
4
;
Hui-hui ZHU
1
,
2
,
3
,
4
;
Ying-dan CHEN
1
,
2
,
3
,
4
;
Xiao-nong ZHOU
1
,
2
,
3
,
4
Author Information
1. National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention
2. WHO Collaborating Centre for Tropical Diseases
3. National Center for International Research on Tropical Diseases, Ministry of Science and Technology
4. Key Laboratory of Parasites and Vector Biology, National Health Commission, Shanghai 200025, China
- Publication Type:Journal Article
- Keywords:
Clonorchiasis;
Treatment;
Mass chemotherapy;
Individual treatment
- From:
Chinese Journal of Schistosomiasis Control
2018;30(5):513-517
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the current drug treatment against clonorchiasis in China, in order to promote the standardization of drug treatment and national deworming for clonorchiasis. Methods All the 10 provinces were enrolled, which reported clonorchiasis in the work report for important helminthiasis in 2016. Then, 20 counties were selected from these 10 provinces. The data on drug treatment including both mass chemotherapy and individual treatment against clonorchiasis were collected and compared. Results All the 10 provinces had no guideline for mass chemotherapy, while only 3 had that for individual treatment against clonorchiasis. Out of 20 counties, only 1 implemented mass chemotherapy. Among these 20 counties, 13 applied praziquantel in individual treatment, while other 7 employed albendazole. In the 12 counties with clear protocol for praziquantel, the total dosage for a man of 60 kg ranged from 3.6 to 18.0 g, the days and times for administration ranged from 1 to 6 and from 3 to 18, respectively. In the 4 counties with clear protocol for albendazole, the total dosage for a man of 60 kg ranged from 0.8 to 8.4 g, the days and times for administration ranged from 2 to 7 and from 2 to 14, respectively. Conclusions Nowadays, the guideline on mass chemotherapy for clonorchiasis is inadequate in China. Although individual treatment is applied in many areas, the protocols vary in drugs, dosage, and days and times for treatment. Thus, the national guideline of mass chemotherapy for clonorchiasis should be established, while the protocols for individual treatment should be standardized.
