Advances in inorganic nanomaterials regulated autophagy in cancer treatment
10.16571/j.cnki.1008-8199.2020.01.015
- VernacularTitle: 基于无机纳米材料调节自噬治疗肿瘤的研究进展
- Author:
Qiao-mei DENG
1
;
Ying LAN
1
;
Guo-he TAN
1
;
Si-jia LIU
1
Author Information
1. School of Basic Medical Sciences, Guangxi Medical University, Nanning 530021, Guangxi, China
- Publication Type:Journal Article
- Keywords:
inorganic nanomaterials;
autophagy;
tumor regulators;
oncotherapy
- From:
Journal of Medical Postgraduates
2020;33(1):83-87
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy represents one of the essential cellular mechanism to maintain homeostasis within cells, performing multiple biological functions during tumorigenesis. Base on the unique physicochemical properties of inorganic nanomaterials, supplemented by easy modification and targeting and so on, they could be used to regulate autophagy, controlling the occurrence and development of tumor and finally achieve treatment. This article primarily reviews the application of several representative inorganic nanomaterials, such as Gold nanoparticles, Silver nanoparticles, Iron oxide nanoparticles, Fullerene C60 nanomaterials, Graphene oxide nanomaterials in regulating autophagy of tumor cells and achieving treatment in recent years.
