Research progress of Faecalibacterium prausnitzii in intestinal diseases
10.16571/j.cnki.1008-8199.2019.06.020
- VernacularTitle: 普拉梭菌在肠道疾病中的研究进展
- Author:
Jing-jing WANG
1
;
Guo-zhong JI
1
;
Bo-ta CUI
1
Author Information
1. Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu,China
- Publication Type:Journal Article
- Keywords:
intestinal diseases;
clinical diagnosis;
treatment
- From:
Journal of Medical Postgraduates
2019;32(6):657-661
- CountryChina
- Language:Chinese
-
Abstract:
Faecalibacterium prausnitzii (F.prausnitzii) is the most abundant intestinal microorganisms in the intestine of healthy adults and has been considered as a biological indicator of human health. In recent years, many studies have shown that F. prausnitzii abundance is reduced in different intestinal diseases. Further more, scholars found F.prausnitzii plays an important role in intestinal mucosal barrier protection and inflammation suppression in intestinal diseases. Therefore, it has been proposed that the abundance of F. prausnitzii may serve as a biomarker to assist in gut diseases diagnostics, providing a new idea for the clinical diagnosis and treatment of intestinal diseases. This article reviews the research progress of F.prausnitziiin in intestinal diseases.