Clinical diagnosis and treatment strategies of pituicytomas
10.16571/j.cnki.1008-8199.2019.05.014
- VernacularTitle: 垂体细胞瘤的诊治及疗效分析
- Author:
Yong TANG
1
;
Chun-yan CHEN
2
;
You-wu FAN
1
;
Han-dong WANG
1
;
Lin ZHU
1
Author Information
1. Department of Neurosurgery, Jinling Hospital, Nanjing University School of Medicine/ General Hospital of Eastern Theater Command, PLA, Nanjing 210002, Jiangsu, China
2. Department of Gastroenterology, Jinling Hospital, Nanjing University School of Medicine/ General Hospital of Eastern Theater Command, PLA, Nanjing 210002, Jiangsu, China
- Publication Type:Journal Article
- Keywords:
pituicytoma;
surgical resection;
hyponatremia;
posterior pituitary
- From:
Journal of Medical Postgraduates
2019;32(5):523-525
- CountryChina
- Language:Chinese
-
Abstract:
Objective Reports are rarely seen on the clinical studies of pituicytomas. This article discusses the clinical diagnosis, treatment strategies, pathological features and postoperative complications of pituicytomas. Methods This retrospective study included 10 cases of pituicytomas treated in our hospital from July 2008 to July 2018. All the patients underwent microsurgery, gross total resection of the tumor in 6 cases and subtotal resection in the other 4. We analyzed the histopathological features, postoperative complications and follow-up data of the patients. Results The tumors were tightly organized morphologically, consisting of bipolar spindle-shaped cells, arranged like crosswise-woven fiber bundles or in a storiform pattern, the cytoplasm stained red and eosinophilic, the nuclei medium-sized, round, oval or spindle shaped, mildly heterotypical, with visible microencapsulation and abundant interstitial blood vessels. The main postoperative complications included insipidus in 8 cases, hyponatremia in 4, decreased visual acuity in 3, hypopituitarism in 2, and intracranial infection in 1. Of the 9 patients followed up, 1 experienced recurrence at 2 years postoperatively and received another surgery, with no more recurrence hitherto. Conclusion Definite diagnosis of pituicytoma depends on pathological examination, and adequate attention should be paid to the prevention and management of such postoperative complications as insipidus and hyponatremia.
