Mechanism of chemotherapy⁃induced tumor metastasis
10.16571/j.cnki.1008-8199.2019.03.018
- VernacularTitle: 化疗促肿瘤转移的机制研究
- Author:
Qiu⁃yue LUO
1
;
Qing ZHANG
2
;
Shao⁃quan XIONG
1
;
Sha ZHOU
3
Author Information
1. Department of Oncology, Chengdu University of Traditional Chinese Medicine Affiliated Hospital, Chengdu 610075,Sichuan, China
2. Chengdu University of Chinese Medicine of Pharmacy, Chengdu 610000,Sichuan,China
3. Department of Gynecology,Panzhihua City Maternal and Child Health Hospital, Panzhihua 617000,Sichuan,China
- Publication Type:Journal Article
- Keywords:
chemotherapy;
metastasis;
seed⁃soil theory;
mechanism
- From:
Journal of Medical Postgraduates
2019;32(3):307-312
- CountryChina
- Language:Chinese
-
Abstract:
Chemotherapy is one of the main treatments for malignant tumors, aiming to kill tumor cells and improve patient survival. However, the new study have found that chemotherapy also promotes distant metastasis of tumors while treating tumor, and the article will give further new meaning to "chemotherapy side effects." On the other hand, tumor metastasis is the main cause of short-term survival of patients. Inhibition of tumor metastasis caused by chemotherapy is a hot topic that should be widely concerned. Modern research suggests that chemotherapeutic drugs promote tumor metastasis by inducing changes in the biological characteristics of tumors and causing a series of "host reactions". The article summarizes the mechanisms of chemotherapy-induced tumor metastasis in combination with the seed and soil theory related to tumor metastasis.