Research progress of Rab25 in tumor metastasis

VernacularTitle: Rab25在肿瘤转移中的研究进展
Author: Lin-xia SONG ¹ ; Shui-ping LV ¹ ; Da-hai LIU ¹ ; Hu MA ¹
Author Information

1. Department of Oncology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou,China
Publication Type:Journal Article
Keywords: Rab25; tumor metastasis; oncogene; tumor suppressor gene
From: Journal of Medical Postgraduates 2019;32(1):99-103
CountryChina
Language:Chinese
Abstract: Metastasis is the main reason that affects the survival and death of cancer patients. In recent years, it has been found that Rab25 is closely related to tumor invasion and metastasis. Rab25 has dual role in tumor metastasis, which can be used as oncogene or tumor suppressor gene. In most tumor types, Rab25 is an oncogene, and only in a few tumors, Rab25 shows tumor suppressor function. However, the dual action mechanism and signal pathway of Rab25 are not very clear. This article summarizes the related research on the role of Rab25 in tumor metastasis.