A Case of Bullous Pemphigoid Associated with Graves' Disease.
- Author:
Hyun Chul PARK
;
Yong Woo CINN
;
Hyang Joon PARK
- Publication Type:Case Report
- Keywords:
Graves' disease;
Bullous pemphigoid;
Autoimmune mechanism
- MeSH:
Adult;
Dermis;
Eosinophils;
Female;
Graves Disease*;
Humans;
Immunoglobulin G;
Pemphigoid, Bullous*;
Skin
- From:Korean Journal of Dermatology
1987;25(3):389-393
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report herein a case of bullous pemphigoid(BP) associated with Graves' disease(GD) The patient was 43-year-old female who had suffered frorn GD for 8 years. She had annular, erythematous atrophic plaques with a margin of small vesicles on the frontal and temporal areas, Histopathologic findings of the skin lesion showed subepiderrnal bulla, and numerous eosinophilic infiltrate in the bulla cavity and dermis. Direct immunofluorescent study of perilesional skin revealed linear IgG deposition at the dermo epidermal junction. We think our case shows a higher than chance association of BP and GD because both are basecl on autoimmune mechanism.
