The research progress of the role of VEGF in endometrium
10.16571/j.cnki.1008-8199.2018.12.022
- VernacularTitle: 血管内皮生长因子在子宫内膜中作用的研究进展
- Author:
Zi-qing NAN
1
;
Hai-ning LV
1
;
Ya-li HU
1
Author Information
1. Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Chinese Academy of Medical Sciences & Graduate School of Peking Union Medical College, Nanjing 210008, Jiangsu,China
- Publication Type:Journal Article
- Keywords:
vascular endothelial growth factor;
endometrium;
menstrual cycle
- From:
Journal of Medical Postgraduates
2018;31(12):1329-1332
- CountryChina
- Language:Chinese
-
Abstract:
Vascular endothelial growth factor (VEGF) plays an important role in the periodic changes of the endometrium under physiological conditions. Under the regulation of various cytokines in different phases of the menstrual cycle, VEGF subtypes bind to their respective tyrosine kinase receptors (VEGFR1, VEGFR2, VEGFR3) , Nrp1 and Nrp2 to participate in physiological processes of the endometrium, such as angiogenesis, changes of vascular permeability, proliferation and migration of endothelial cells and non-endothelial cells, etc. This article summarizes the research progress of the function of various VEGF subtypes in the normal periodontal changes of the endometrium.
