Blood purification therapy in children with acute liver failure
- Author:
Liang PEI
1
;
Chun-feng LIU
1
Author Information
- Publication Type:Journal Article
- Keywords: chlid; acute liver failure; blood purification
- From: Chinese Journal of Practical Pediatrics 2019;34(12):1001-1005
- CountryChina
- Language:Chinese
- Abstract: Acute liver failure(ALF)is a life-threatening clinical syndrome in children,which has a high mortality. Extracorporeal liver support systems include bioartificial liver,nonbioartificial liver and hybrid artificial liver,with the aim of supporting children with ALF,as a bridge to recovery or liver transplantation. The theoretical basis of non-bioartificial liver support system is blood purification. Although biochemical efficacy has been demonstrated by these devices,the effect on the final prognosis has been unclear. Compared with adults,there are less data on the treatment for children with ALF,and some new blood purification modes and combined blood purification modes have shown potential in the treatment of ALF in recent years. The aim of this review is to introduce the practice of blood purification and to provide references for the treatment of children with ALF.
