- Author:
Xin-lei JIA
1
;
Heng-miao GAO
1
;
Su-yun QIAN
1
Author Information
- Publication Type:Journal Article
- Keywords: sepsis; blood purification; therapy
- From: Chinese Journal of Practical Pediatrics 2019;34(12):984-989
- CountryChina
- Language:Chinese
- Abstract: Sepsis is a life-threatening organ dysfunction caused by the body's dysfunctional response to infection. There is currently no definitive symptomatic treatment for sepsis inflammatory response in the clinic. Blood purification treatment exerts immunomodulatory effects by non-specifically eliminating endotoxin and/or inflammatory mediators and shows a good prospect of application in sepsis. However,most studies on the treatment of sepsis with blood purification have not shown significant improvement in patients' prognosis. This article reviews the research progress of immunoregulation mechanism of blood purification therapy for sepsis,as well as the advantages and disadvantages of different blood purification methods.