Comparative study on volatile oil in Rhizoma chuanxiong by steam distillation and supercritical fluid extraction
10.3969/j.issn.1006-0111.201907022
- VernacularTitle:川芎药材超临界CO2萃取与水蒸气蒸馏提取挥发油比较研究
- Author:
Peng DENG
1
;
Feixue WEI
1
;
Yi WEN
1
;
Baoyi WANG
1
;
Shan CHEN
1
Author Information
1. Eight plus one Pharmaceutical Co.,Ltd, Guilin 541000, China.
- Keywords:
supercritical fluid extraction；steam distillation;
Rhizoma Chuanxiong;
volatile components
- From:
Journal of Pharmaceutical Practice
2020;38(2):152-155
- CountryChina
- Language:Chinese
-
Abstract:
Objective To clarify the influence of the extraction process on its active ingredients by comparing the volatile oils of Rhizoma Chuanxiong obtained under different processes. Methods The volatile oil of Rhizoma Chuanxiong was extracted by supercritical CO2 extraction (SFE) and steam distillation. The main chemical components and relative contents were identified by gas chromatography-mass spectrometry (GC-MS). Results A total of 18 common components were identified in the volatile oil samples of Chuanxiong from the two methods. In steam distillation samples, main components included phthalides (61%), monoterpenoids (25%) and sesquiterpenes (10%). In SFE samples, phthalides (97%) were major components, followed by monoterpenoids (1%),sesquiterpenes (0.4%) and other minor components. Conclusion The steam distillation retains highly volatile components in Rhizoma chuanxiong such as monoterpenoids and sesquiterpenes. For SFE approach, the phthalides were extracted more efficiently compared with other components. The effect of the extraction process on the active ingredients should be fully considered in obtained products of Rhizoma chuanxiong since the difference in constituents may result in varied effects.
