Two Cases of Transfusion Related Acute Lung Injury.
10.4046/trd.2006.61.5.473
- Author:
Kyoung Ju LEE
1
;
Hye Ok KIM
;
Jung Ha KIM
;
Eun Sil HA
;
Jin Yong JUNG
;
Seung Hyeun LEE
;
Se Joong KIM
;
Moon Kyung JU
;
Eun Joo LEE
;
Eun Hae KANG
;
Ki Hwan JUNG
;
Sung Yong LEE
;
Sang Yeub LEE
;
Je Hyeong KIM
;
Chol SHIN
;
Jae Jeong SHIM
;
Kwang Ho IN
;
Kyung Ho KANG
;
Se Hwa YOO
Author Information
1. Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea. dreamnet@dreamwiz.com
- Publication Type:Case Report
- Keywords:
Blood transfusion;
Pulmonary reaction;
Acute lung injury;
TRALI
- MeSH:
Acute Lung Injury*;
Blood Group Incompatibility;
Blood Transfusion;
Dyspnea;
Fever;
Hepatitis;
Humans;
Mortality;
Thorax
- From:Tuberculosis and Respiratory Diseases
2006;61(5):473-478
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Transfusion related acute lung injury (TRALI) is a serious, potentially life-threatening complication of transfusion therapy that is sometimes under diagnosed and under reported. Patients with TRALI present with dyspnea/respiratory distress and fever. The symptoms, signs and chest radiological findings in TRALI are similar to transfusion associated circulatory overload, which makes it is difficult to distinguish it from circulatory overload. Although the mortality rate in cases of TRALI is relatively low, TRALI is the third most common cause of fatal transfusion reactions next to ABO blood type incompatibility and hepatitis. Mild-to-moderate cases of TRALI may be misdiagnosed as volume overload. Recently, we encountered two cases where the patients suffered from dyspnea and fever after a transfusion. and review of the relevant literature.
