Pathological Characteristics of Endometrium in Abnormal Uterine Bleeding and the Relationship between Pathology and Obesity
- VernacularTitle:异常子宫出血的子宫内膜病理特点及与肥胖的关系
- Author:
Yu ZHANG
1
;
Juan CHENG
1
;
Qing-jian YE
1
;
Xiao-mao LI
1
Author Information
1. Departments of Gynecology，The Third Affiliated Hospital of Sun Yat-sen University，Guangzhou 510630
- Publication Type:Journal Article
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2019;40(2):316-322
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To investigate the endometrial pathological composition in abnormal uterine bleeding（AUB），and whether it related to age，body mass index，waist circumference or waist-hip ratio.【Methods】From January 2017 to June 2017，206 patients with AUB underwent diagnostic curettage or hysteroscopy and endometrial biosy in the daytime operating room of the Third Affiliated Hospital of Sun Yat- sen University were included ，and age，height， weight ，waist circumference ，hip circumference and endometrial pathology were collected and analyzed statistically.【Results】① The proportions of Normal endometrium（NE），Disorder Proliferative Endometrium（DPE），Endometrial Polyp（EP），Endometrial Hyperplasia without atypia （EH without atypia），Endometrial Hyperplasia with atypia （EH with atypia），and Endometrial Cancer（EC，type I）were 32.52%，8.25%，6.31%，40.77%，9.22% and 2.91% respectively in endometrial pathological grouping. ②The age of EC group was 50.0（S=7.3）years old，which was older than that of NE group 42.0（S=13.0，P<0.01）. ③The abdominal circumference of EC group（89.0±4.9）cm were higher than that of NE group（81.4±5.4）cm（P<0.01）. WHR of EH with atypia group and EC group were（0.877±0.035）and（0.912±0.042） respectively，which were higher than that of NE group［（0.847±0.036）；P<0.01，P<0.01］.【Conclusions】About half of patients with abnormal uterine bleeding have endometrial hyperplasia，and the proportion of endometrial cancer is nearly 3%，both of which are associated with central obesity（such as increased waist circumference and/or waist-to-hip ratio）.
