Sleep Status of Patients with Chronic Hepatitis B Virus Infection
- VernacularTitle:慢性乙型肝炎病毒感染患者睡眠情况调查
- Author:
Xiao-yan ZHENG
1
;
Ming-xue YU
1
;
Yu-sheng JIE
1
;
Jing CAO
1
;
Liu-ping SHA
1
;
Yu-tian CHONG
1
;
Yu-feng ZHANG
1
;
Ji-hui2 WANG
2
Author Information
1. Department of Infectious Disease,Sun Yat-sen University,Guangzhou 510530,China
2. Department of Psychiatry,The Third Affiliated Hospital,Sun Yat-sen University,Guangzhou 510530,China
- Publication Type:Journal Article
- Keywords:
HBV, sleep disorder, investigation
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2020;41(1):95-102
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】To investigate the sleep status of patients with chronic HBV infection【Methods】From January 2019 to June 2019 ,353 patients with chronic hepatitis B virus infection in the outpatient department of the Third Affiliated Hospital of Sun Yat-sen University,using the sleepiness scale,insomnia scale,sleep quality scale,anxiety self- rating form and depression self- evaluation ,patients were scored and grouped according to sleep grading criteria. Patients were collected for gender,age,disease diagnosis,antiviral therapy,and educational level. Chi-square correlation test and multivariate logistic regression were applied to analyze the influencing factors of sleep. 【Results】 The overall sleepiness rate was 47.88%. The overall insomnia rate was 53.26%. There were 6.8% patients who had poor sleep quality. The risk factor of lethargy was the degree of anxiety(P = 0.000,OR = 3.076,95% CI 1.706~5.545). The risk factor of insomnia was anxiety(P = 0.000,OR = 14.693,95% CI 5.046~42.782)and depression(P = 0.002,OR = 2.279,95% CI1.340~3.877). The risk factor of sleep quality was anxiety(P = 0.000,OR = 9.990,95% CI 4.031~24.758).【Conclusions】
Patients with chronic HBV infection have a high proportion of subjective sleep disorders. The main influencing factor is mental state of the patient. A full understanding of the patients′ sleep status will help the patients′ treatment.