Progress on application of marginal donor liver and organ function maintenance in liver transplantation
10.3969/j.issn.1674-7445.2020.02.020
- VernacularTitle:边缘供肝及器官功能维护在肝移植中的应用进展
- Author:
Qingqing DAI
1
;
Hongchuan ZHAO
;
Guobin WANG
;
Fan HUANG
Author Information
1. Organ Transplantation Center, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China
- Publication Type:Research Article
- Keywords:
Liver transplantation;
Marginal donor liver;
Organ function maintenance;
Extracorporeal membrane oxygenation (ECMO);
Mechanical perfusion;
Hypothermia
- From:
Organ Transplantation
2020;11(2):304-
- CountryChina
- Language:Chinese
-
Abstract:
Liver transplantation is the only effective method to treat various end-stage liver diseases. The shortage of standard donor liver is the main factor limiting the development of liver transplantation, whereas the application of marginal donor liver has significantly expanded the source of donor liver. New technologies, such as extracorporeal membrane oxygenation (ECMO), mechanical perfusion and hypothermia, can significantly improve the quality of marginal donor liver, which has good development prospects in organ function maintenance. This article reviews the common types of marginal donor liver and the application of related novel technologies in the maintenance of marginal donor liver function.