Association between adverse childhood experiences and adolescent depression: a Meta-analysis
10.16835/j.cnki.1000-9817.2019.08.016
- VernacularTitle:童年期不良经历与青少年抑郁关系队列研究的Meta分析
- Author:
XIE Guodie, HAN Azhu, CHEN Liru, SU Puyu
1
Author Information
1. Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei (230032),China
- Publication Type:Journal Article
- Keywords:
Depression;
Mental health;
Cohort studies;
Meta-analysis;
Adolescent
- From:
Chinese Journal of School Health
2019;40(8):1177-1181
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To summarize the existing cohort study evidence between adverse childhood experience(ACEs) and adolescent depression, to explore the influence of ACEs on adolescent depression, so as to provide evidence for the prevention of adolescent depression.
Methods:Chinese and English literatures on the cohort study on the correlation between ACEs and adolescent depression published by WanFang, VIP databases, CNKI, CBM, PubMed and Web of Science were searched. We only selected orginal articles that their either reported on Chinese and English retrieval words of "adverse childhood experiences" "ACE" "abuse" "maltreat" "mistreat" "neglect" "bully" "bullying" "family dysfunction" "family violence" "adversities" "trauma" "victimization" "victim" "adverse events" "adverse experiences" "longitudinal" "follow-up" "prospective" "cohort" "depression" "depressive". Meta-analysis was performed on the literatures that met the inclusion criteria, and statistical analysis was conducted using Stata software.
Results:Twelve references (11 in English and 1 in Chinese) were included in the Meta-analysis, and the results showed that ACEs were positively correlated with adolescent depression (pooled OR=1.75，95%CI=1.43-2.15). Among them, The effect of neglect was most prominent (pooled OR=2.42, 95%CI=1.31-4.46) while the influence of abuse was least strong (pooled OR=1.77, 95%CI=1.25-2.52). The pooled odds ratio associated with bully was 2.09 with the 95% confidence intervals from 1.38 to 3.16. The pooled odds ratio of boys is greater than girls(boys: pooled OR=3.77, 95%CI=2.31-6.15; girls: pooled OR=1.44, 95%CI=1.04-2.01). Funnel plot and Egger test suggested publication bias in the included literatures, and the sensitivity analysis indicated that the meta analysis results were relatively stable.
Conclusion:The adverse childhood exprience is positively associated with adolescent depression.Adolescent depression is strongly affected by neglected,and is least affected by abuse.
