Comparative Analysis of Volatile Oil Constituents of Glehnia littoralis from Different Producing Areas
- VernacularTitle:不同产地北沙参药材的挥发油成分比较分析
- Author:
Huiming WANG
1
;
Zhiqiang LYU
1
;
Hao’er ZHANG
2
;
Dongqi PAN
1
;
Pengrui WANG
2
;
Hongbing LIU
2
Author Information
1. Drug Purchase Office，the Affiliated Hospital of Qingdao University，Shandong Qingdao 266000，China
2. School of Pharmacy，Ocean University of China，Shandong Qingdao 266003，China
- Publication Type:Journal Article
- Keywords:
Glehniae littoralis;
Producing area;
Volatile oil;
Constituents;
GC-MS;
Falcarinol;
Chemical marker
- From:
China Pharmacy
2019;30(22):3109-3112
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE： To compare the difference in volatile oil constituents of Glehniae littoralis from 3 producing areas as Shandong Laiyang， Hebei Anguo， Inner Mongolian Chifeng. METHODS： The method of steam distillation was used to extract the volatile oil of G. littoralis from different areas and calculate the extraction rate. The constituents of volatile oil were analyzed by using GC-MS. The data was corrected by Xcalibur chemical workstation. The constituents were searched by NIST 11.0 mass spectrometry database （matching degree ＞800）， and the relative mass fraction of each chemical constituent was obtained by peak area normalization. RESULTS： The extraction rate of volatile oil in G. littoralis from Laiyang was 0.013％， which was far lower than G. littoralis from Anguo （0.099％） and G. littoralis from Chifeng （0.105％）. There were 15， 18 and 27 constituents identified in volatile oil of G. littoralis from 3 producing areas； the relative mass fractions were 89.29％， 96.76％， 94.53％. Falcarinol was a common compound with the highest relative mass fraction of the volatile oil of G. littoralis from different producing areas； the relative mass fractions were 69.79％， 90.89％ and 71.04％， respectively. Fatty acids were rich in the sample from Laiyang， while C15H24 sesquiterpenoids were rich in the other samples from Anguo and Chifeng. CONCLUSIONS： Volatile oil of G. littoralis could be used as potential chemical markers to distinguish different producing areas due to their significant differences in chemical components.
