Application of Hierarchical Weighted TOPSIS to Evaluate Rational Drug Use of Saxagliptin in a Hospital
- VernacularTitle:分层加权TOPSIS法在某院沙格列汀合理用药评价中的应用
- Author:
Yan LI
1
,
2
;
Aizong SHEN
2
;
Pengli ZHU
2
;
Wan ZHOU
3
;
Ming FANG
2
;
Weijian NI
2
;
Wei WEI
1
;
Liqin TANG
1
Author Information
1. Institute of Clinical Pharmacology，Anhui Medical University & Key Lab of Anti-inflammatory and Immune Medicine，Ministry of Education，Hefei 230032，China
2. Dept. of Pharmacy，the First Affiliated Hospital of University of Science and Technology of China & Anhui Provincial Hospital，Hefei 230001，China
3. Dept. of Endocrinology，the First Affiliated Hospital of University of Science and Technology of China & Anhui Provincial Hospital，Hefei 230001，China
- Publication Type:Journal Article
- Keywords:
Saxagliptin;
AHP;
TOPSIS method;
Rational evaluation of drug use
- From:
China Pharmacy
2020;31(5):627-632
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE：To provide method reference for scientifically eva luating the rationality of the use of saxagliptin . METHODS：Based on the drug instructions ，clinical guidelines ，clinical pathways ，related references ，clinical endocrinology department and pharmaceutical experts of a hospital jointly discussed and formulated the evaluation criteria for the rationality of the use of saxagliptin. AHP method was used to assign weights to various indexes of evaluation criteria ；TOPSIS method was used to analyze the use of saxagliptin of 106 cases in the hospital during Nov. 2018-Apr. 2019 retrospectively and evaluate rational drug use. RESULTS ：A total of 6 primary indicators and 12 secondary indicators were established. The first three indicators with a relatively high index weight were indications （with a weight of 0.25），dose and adjustment of administration （with a weight of 0.21）and frequency of administration （with a weight of 0.15）. Among 106 cases，39.6％ of drug use were reasonable ，51.0％ were basically reasonable and 9.4％ were unreasonable. Evaluation results made by weighted TOPSIS were consistent with the actual situation. CONCLUSIONS ：TOPSIS method weighted by AHP is reasonable and feasible for evaluating the rationality of saxagliptin use.
