Analysis of the first cluster of cases in a family of novel coronavirus pneumonia in Gansu Province
10.3760/cma.j.cn112150-20200204-00065
- VernacularTitle: 甘肃省首起新型冠状病毒肺炎家庭聚集性疫情分析
- Author:
Shaoli BAI
1
;
Jianyun WANG
1
;
Yingquan ZHOU
1
;
Desheng YU
2
;
Xiaomin GAO
1
;
Lingling LI
1
;
Fan YANG
1
Author Information
1. Department of Infectious Disease, Lanzhou Municipality Pulmonary Hospital, Lanzhou 730046, China
2. Gansu Province Center for Disease Control and Prevention, Lanzhou 730000, China
- Publication Type:Journal Article
- Keywords:
Novel coronavirus pneumonia;
Family cluster;
Immunologlobulin M;
Polymerase chain reaction
- From:
Chinese Journal of Preventive Medicine
2020;54(4):E005-E005
- CountryChina
- Language:Chinese
-
Abstract:
The epidemiological history and clinical characteristics of 7 cases of COVID-19 and 1 case of close contact in the first family aggregation epidemic of COVID-19 in Gansu Province were analyzed. The first patient A developed on January 22, 2020, with a history of residence in Wuhan, and confirmed severe cases of NCP on January 24, 2020; patient B, on January 23, 2020, diagnosed on January 31, severe cases; patient C, asymptomatic, diagnosed on January 27; patient D, asymptomatic, diagnosed on January 27; patient E, on January 24, diagnosed on January 28; patient F, asymptomatic, diagnosed on January 31; Patient G was asymptomatic and was diagnosed on January 31. In close contact, H was asymptomatic, PCR test was negative and asymptomatic, and he was discharged early. Among the 7 patients, 1 case died of (B) aggravation, and the other patients' condition was effectively controlled after active treatment. Except for the discharged cases, 5 cases were positive for COVID-19 specific IgM antibody and 1 case was negative. In this clustering outbreak, 4 patients remained asymptomatic, but PCR and IgM antibodies were positive, indicating that asymptomatic patients may be the key point to control the epidemic. Specific IgM antibody screening for patients whose pharyngeal swab nucleic acid test is negative but with ground glass-like lung lesions is very important for early detection and early isolation.
