Anti-TNF-α Monoclonal Antibody for Ulcerative Colitis：Methodology/Reporting Quality Reevaluation of Meta-analysis/ Systematic Evaluation
- VernacularTitle:抗肿瘤坏死因子α单克隆抗体治疗溃疡性结肠炎的Meta分析/系统评价的方法学/报告质量再评价
- Author:
Zongyao HUANG
1
,
2
,
3
,
4
;
Liang HUANG
1
,
2
,
3
,
4
;
Jin ZENG
1
;
Mao LIN
1
,
2
,
3
,
4
;
Linli ZHANG
1
,
2
,
3
Author Information
1. West China Pharmaceutical College，Sichuan University，Chengdu 610041，China
2. Dept. of Pharmacy，West China Second Hospital，Sichuan University，Chengdu 610041，China
3. Evidence-based Pharmaceutical Center，West China Second Hospital，Sichuan University，Chengdu 610041，China
4. Key Laboratory of Birth Defects and Related Diseases of Women and Children，Ministry of Education，Chengdu 610041，China
- Publication Type:Journal Article
- Keywords:
Anti-TNF-α monoclonal antibody;
Ulcerative colitis;
Systematic reevaluation;
Methodological;
Reporting;
AMSTAR scale;
PRISMA statement
- From:
China Pharmacy
2019;30(7):975-979
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE： To conduct methodology/reporting quality reevaluation for Meta-analysis/systematic evaluation of anti-TNF-α monoclonal antibody in the treatment of ulcerative colitis. METHODS： Retrieved from the Cochrane library， PubMed， Embase， CBM， Wanfang database and CNKI during data base establishment to Nov. 2018， Meta-analysis/systematic evaluations of anti-TNF-αmonoclonal antibody in the treatment of ulcerative colitis were collected. After data extraction of literatures that meet the inclusion criteria， methodological quality and reporting quality of included studies were evaluated by using AMSTAR scale and the PRISMA statement. RESULTS： Fourteen literatures of Meta-analysis/systematic evaluation were included. The average score of AMSTAR methodology quality （full score of 11 points） was 6.89， with medium methodological quality. PRISMA score （full score of 27 points） ranged from 15 to 26.5. CONCLUSIONS： Meta-analysis/systematic evaluations of anti-TNF-α monoclonal antibody for ulcerative colitis have poor methodological and reporting quality.
