Study on the Chemical Constituents in the Ethyl Acetate Extract of Balanophora involucrate
- VernacularTitle:筒鞘蛇菰乙酸乙酯部位的化学成分研究
- Author:
Jiangchun WEI
1
;
Guoqing LONG
1
;
Anhua WANG
1
;
Jingming JIA
1
Author Information
1. College of TCM，Shenyang Pharmaceutical University，Shenyang 110016，China
- Publication Type:Journal Article
- Keywords:
Balanophora involucrate;
Chemical constituent;
Structure identification;
Dihydroflavones;
Ethyl acetate extract part
- From:
China Pharmacy
2019;30(7):922-926
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE： To study the chemical constituents in the ethyl acetate extract of Balanophora involucrate， and to provide reference for further enriching chemical constituent of the plant and the development and utilization of B. involucrate. METHODS： The whole plant of B. involucrate was extracted with 75％ ethyl alcohol. The extraction was carried out by petroleum ether， dichloromethane， ethyl acetate and n-butyl alcohol in turn. The chemical compounds from ethyl acetate extract part were isolated and purified by silica gel column， gel column and semi-preparative HPLC. The structures were identified on the basis of spectral spectrum （mass spectrum， hydrogen spectrum and carbon spectrum） data and literature reports. RESULTS： Thirteen compounds were isolated from ethyl acetate extract part of B. involucrate， identified respectively as pyracanthoside （1）， 5，7，3′ ，5′ -tetrahydroxyflavanone （2）， naringenin （3）， homoeriodictyol （4）， hesperetin （5）， sakuranetin （6）， eriodyctiol （7）， aureusidin-6-O-β-D-glucopyranoside （8）， penicillic acid （9）， dihydropenicillic acid （10）， 2-methyl-3-foroic acid （11）， 5-hydroxymaltol （12） and 5， 7-dyhydroxy chromone （13）. Most of them were dihydroflavones. Compounds 2 to 13 are isolated from Balanophora genus for the first time. CONCLUSIONS： The study enriched the chemical constituents of the Balanophora genus and lays foundation for quality evaluation of B. involucrate.
