Simultaneous Determination of 27 Kinds of Heavy Metals and Trace Elements in Halloysitum album by ICP-MS
- VernacularTitle:ICP-MS法同时测定白石脂药材中27种重金属及微量元素的含量
- Author:
Renyuan ZHU
1
;
Liangliang JI
1
;
Xiaoping ZHANG
1
;
Guoyu QIU
1
;
Xiao MA
2
Author Information
1. Lanzhou Institute for Food and Drug Control，Lanzhou 730050，China
2. Gansu Institute for Drug Control/Gansu Inspection and Testing Technical Engineering Laboratory for Chinese Herbal and Tibetan Medicine，Lanzhou 730070，China
- Publication Type:Journal Article
- Keywords:
Halloysitum album;
Different origins;
ICP-MS;
Heavy metals;
Trace elements
- From:
China Pharmacy
2019;30(10):1380-1385
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE： To establish a method for simultaneous determination of 27 kinds of heavy metals and trace elements in Halloysitum album from different origins. METHODS： The sample was dissolved by wet digestion. Using inductively coupled plasma mass spectrometry （ICP-MS）， carrier gas was argon and collision gas was helium； plasma gas flow rate was 15.0 L/min； flow rate of carrier gas was 1.17 L/min and collision gas flow rate was 5.0 mL/min； atomizer was Barbinton， and sampling depth was 8.0 mm； atomizing chamber temperature was 2 ℃； radio frequency power was 1.3 kW； peristaltic pump revolutions was 30 r/min. In full quantitative analysis model， the number of test points was 3， the analysis time was 0.1 s， the repetition was 3 times， clustering analysis was conducted by using PASW Statistics 18.0 software. RESULTS： The linear range of 27 kinds of heavy metals and trace elements were 0-200 μg/L（r≥0.996 5）； the quantitative limit was 0.003 41-75.485 μg/L and the detection limit was 0.001 1-24.350 0 μg/L. RSDs of precision， stability and repeatability tests were all less than 7％； average recovery was 72.3％- 129.1％ （RSD was 0.9％-9.4％， n＝6）. The content of Al was 0.01-123 220.20 mg/kg， and Al was the element with the highest content. Li， Na， Mg， K， Ca， V， Mn， Fe， Co， Ni， Zn， Ga， Se， Rb， Sr， Ba and U were the principal components of trace elements and could be used as characteristic elements； 26 batches of Halloysitum Album samples could be grouped into 4 categories. CONCLUSIONS： The established method is simple， fast and highly sensitive， can improve the precision and accuracy of test results， and it is suitable for the determination of heavy metals and trace elements in Halloysitum album.
