The Efficacy of 99mTc-DMSA SPECT in Diagnosis of Renal Scarringn of Vesicoureteral Reflux in Children.
- Author:
Hyun Cheul NAM
1
;
Tae Gyun KWON
;
Sung Kwang CHUNG
Author Information
1. Department of Urology, Kyungpook National University, School of Medicine, Taegu, Korea.
- Publication Type:Original Article
- Keywords:
Renal scar;
Vesicoureteric reflux;
99mTc-DMSA planar 99mTc-DMSA SPECT
- MeSH:
Child*;
Cicatrix;
Diagnosis*;
Humans;
Hypertension, Renal;
Kidney Failure, Chronic;
Retrospective Studies;
Sensitivity and Specificity;
Succimer;
Technetium Tc 99m Dimercaptosuccinic Acid*;
Tomography, Emission-Computed, Single-Photon*;
Vesico-Ureteral Reflux*
- From:Korean Journal of Urology
1998;39(7):627-632
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The diagnosis of renal scarring is very important for the pediatric patient because it has been associated with the later development of hypertension, renal failure, and end-stage kidney disease. Recent studies indicate that the sensitivity and specificity of the99mTc-DMSA single photon emission computerized tomography (SPECT) is better than IVP, USG, and 99mTC-DMSA Planar ThG Purpose Of this Study iS tO Compare 2 types Of 9%nTh DMSA renal scan(planar and SPECT) and IVP/USG in the diagnosis of renal scars. MATERIALS AND METHOD: We reviewed retrospectively the data of 49 children(72 renal units) with vesicoureteral reflux(VUR) who underwent renal cortical imaging with IVP/USG from January 1987 to August 1996. Patient ages ranged from 3 months to 14 years with a mean age 3.7 years. There were 17 boys and 12 girls(44 venal units) with 99mTc-DMSA planar with IVP/USG, and 12 boys and 8 girls(28 renal units) with 99mTc-DMSA SPECT with IVP/USG. RESULTS: The 99mTc-DMSA planar imaging identified 94.7% sensitivities while 99mTC-DMSA SPECT imaging identified 96.3% Sensitivities. And the IVP/USG identified 75.3% sensitivities. CONCLUSIONS: Recently, the 99mTc-DMSA renal scan has replaced IVP/USG in detecting renal scarring. And we show that 99mTc-DMSA SPECT studies are superior to IVP/USG, 99mTc-DMSA planar studies in detecting renal scarring. We believe that the role of 99mTc-DMSA SPECT will become increasingly important in detecting renal scarring of VUR.
