Three-dimensional visualization technology for precise diagnosis and treatment of primary liver cancer: A Meta-analysis
10.19538/j.cjps.issn1005-2208.2019.08.23
- Author:
Wei-qi ZHANG
1
;
Chi-hua FANG
1
Author Information
1. The First Department of Hepatobiliary Surgery,Zhujiang Hospital,Southern Medical University, Guangdong Provincial Clinical and Engineering Center of Digital Medicine Guangzhou 510282,China
- Publication Type:Journal Article
- Keywords:
three-dimensional visualization technology;
two-dimensional imaging;
primary liver cancer;
hepatectomy;
Meta-analysis;
systematic evaluation
- From:
Chinese Journal of Practical Surgery
2019;39(08):854-860
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To systematically review the effectiveness and safety of three-dimensional visualization technology(3 DVT) for precise diagnosis and treatment of primary liver cancer(PLC). METHODS: The cohort studies regarding using3 DVT in precise diagnosis and treatment of PLC were collected by searching several national and international online databases. The retrieval time was from inception of the database to June 2019. Two reviewers independently screened the literatures, extracted data and evaluated the methodological quality of included studies. Then, meta-analysis was performed by using RevMan 5.3 software. RESULTS: A total of 8 studies were finally included involving 533 patients, with 263 cases in 3 DVT group and 270 in two-dimensional(2D) imaging group. The results of meta-analysis showed that in 3 DVT group, compared with 2 D imaging group, the intraoperative blood loss was reduced(MD=-76.00, 95%CI-127.25—-24.74, P=0.004);the operative time was shortened(MD=-44.81, 95%CI-64.64—-24.98, P<0.00001);the incidence of postoperative complications was decreased(OR=0.46, 95%CI 0.28—0.77, P=0.003);the postoperative liver function index albumin(ALB) was elevated(MD=1.89, 95%CI0.74—3.04, P=0.001);the hospitalization time was shortened(MD=-2.47,95% CI-3.25—-1.68),P<0.00001);the recurrence rate of liver cancer was reduced after 6 months to 1 year follow-up(OR=0.44, 95% CI 0.22—0.88, P=0.02).There were no statistical differences between the two groups in respects of the incidence of postoperative liver function index alanine aminotransferase(ALT), aspartate aminotransferase(AST), total bilirubin(TBIL) as well as the survival rate of liver cancer after 6 months to 1 year follow-up(all P>0.05). CONCLUSION: The application of3 DVT in precise diagnosis and treatment of PLC is safe and effective, and it can effectively reduce the intraoperative blood loss and the incidence of postoperative complications, accelerate the recovery of postoperative liver function, shorten the operation time and hospitalization time, and reduce the recurrence rate of liver cancer in short-term follow-up.
