Observation on the efficacy of motherwort injection in the treatment of abnormal uterine bleeding-ovulatory dysfunction
- Author:
Wan-jing LI
1
;
Wan-ting XIA
1
;
Hang ZHOU
1
;
Yong-wen LI
;
Jing YUAN
;
Xiao-lin XIE
;
Fang HE
;
Qian ZENG
1
Author Information
- Publication Type:Journal Article
- Keywords: motherwort injection; abnormal uterine bleeding-ovulatory dysfunction; clinical efficacy observation
- From: Chinese Journal of Practical Gynecology and Obstetrics 2019;35(10):1150-1155
- CountryChina
- Language:Chinese
- Abstract: OBJECTIVE: To observe the clinical efficacy of motherwort injection in the treatment of abnormal uterine bleeding-ovulatory dysfunction(AUB-O),and provide data support for broadening the clinical application range of motherwort injection.METHODS: A multicenter,randomized,prospective study was used.The patients who were diagnosed with AUB-O in Hospital of Chengdu University of Traditional Chinese Medicine in 2018 were randomly divided into the control group and the experimental group according to random numbers.There were 75 cases in the experimental group,7 cases were lost,and 68 cases were the final cases;another 75 cases were in the control group,4 cases were lost,and there were 71 cases in the end.In the control group,only the tranexamic acid was given.On the basis of this,the experimental group was given intramuscular injection of motherwort injection 2 mL/time,b.i.d.,for 3 consecutive days.The clinical TCM symptom scores,blood loss,blood routine,coagulation function,endometrial thickness and effective rate were compared between the two groups.All data were statistically analyzed using IBM SPSS 21.0.RESULTS: After treatment,the total effective rate of the experimental group was 97.06%,which was significantly better than that(84.51%)of the control group(P<0.05).TCM syndrome scores of Qi stagnation and blood stasis of the experimental group was significantly lower than those in the control group(P<0.05).TCM syndrome scores of damp-heat stagnation of the experimental group was significantly lower than those in the control group(P<0.05).There was no significant difference in the amount of bleeding between the two groups on the first day after treatment(P>0.05),but on the 2nd day and the 3rd day after treatment,the difference was statistically different(P<0.05),and the cumulative amount of bleeding after 3 days of treatment was statistically different(P<0.05).The endometrial thickness of the experimental group was lower than that of the control group(P<0.01).CONCLUSION: Motherwort injection combined with basic therapy is effective in the treatment of AUB-O.
