Effects of two kinds of conizations of cervix in the treatment of precancerous lesions of the cervix and its influence on fertility preservation
- Author:
Fan-li SHI
1
;
Min WANG
1
;
Hong-yan YIN
1
;
Zhi ZENG
1
Author Information
- Publication Type:Journal Article
- Keywords: precancerous lesions of the cervix; C-E-CKC; CKC; fertility preservation
- From: Chinese Journal of Practical Gynecology and Obstetrics 2019;35(06):702-705
- CountryChina
- Language:Chinese
- Abstract: OBJECTIVE: To discuss the effects of C-E-CKC and CKC in treating precancerous lesions of the cervix(CIN2,CIN3)and its influence on fertility preservation.METHODS: Select 138 patients who accepted conization of cervix with CIN2,CIN3 from January 2013 to January 2017 in our hospital,the C-E-CKC group consisted of 81 cases and the CKC group 57 cases.Compare the average operation time,the average intraoperative blood loss,cone length,the preoperative and postoperative pathological coincidence rates,the positive rate of the tangent margin,the rate of the recurrence rate,postoperative complications rate,and the pregnancy situation and outcome of two groups.RESULTS: The average operation time of C-E-CKC and CKC group was(29.60±5.98)min and(33.67±5.95)min,respectively,and the average intraoperative blood loss was(14.01±12.00)mL and(19.56±16.10)mL.In C-E-CKC group,the conical excision length of type I,Ⅱ and Ⅲ transformation zone was(1.56±0.18)cm,(1.58±0.24)cm and(1.67±0.29)cm,while in CKC group,it was(1.71 ±0.34)cm,(1.80±0.37)cm and(2.20±0.27)cm,and the differences between the groups were statistically significant(P<0.05).There was no significant difference in the preoperative and postoperative pathological coincidence rates,the positive rate of the tangent margin,the recurrence rate,postoperative complications rate or the pregnancy outcome between the two groups(P>0.05).CONCLUSION: The two methods are both safe and effective for treating precancerous lesions of the cervix(CIN2,CIN3).C-E-CKC is with shorter operation time,less intraoperative bleeding and smaller excision of cervical tissue,and the damage to cervix is smaller,which is more suitable for patients to preserve fertility.
