Relation between coagulation parameters and pelvic adhesions in endometriosis
- Author:
Qiao LIN
1
;
Shao-jie DING
2
;
Xuan CHE
2
;
Tian-tian LI
2
;
Xin-mei ZHANG
2
Author Information
- Publication Type:Journal Article
- Keywords: endometriosis; coagulation; fibrinogen; adhesion
- From: Chinese Journal of Practical Gynecology and Obstetrics 2019;35(06):677-680
- CountryChina
- Language:Chinese
- Abstract: OBJECTIVE: To investigate the correlation between coagulation parameters and pelvic adhesions in endometriosis.METHODS: The clinical data of 408 patients with endometriosis who underwent surgery in Women's Hospital School of Medicine Zhejiang University from June 2016 to February 2018 were retrospectively analyzed to evaluate the correlation between coagulation parameters and the severity of pelvic adhesions.RESULTS: In endometriosis cases,the levels of plasma fibrinogen(FIB)in patients with pelvic adhesions were significantly shorter than those without pelvic adhesions[median:3.1 g/L(range:2.7-4.5 g/L)vs. 2.8 g/L(range:2.6-3.2 g/L),respectively;P<0.01],the plasma prothrombin time(PT)in patients with pelvic adhesions were significantly shorter than those without pelvic adhesions[median:12.9 s(range:12.5-13.3 s)and 13.1 s(range:12.7-13.5 s),respectively;P<0.01],while there was no difference in the levels of platelet count(PLT)or activated partial prothrombin time(APTT)(P>0.05). FIB was positively correlated with pelvic adhesion scores(r=0.248,P<0.01).In the judgment of pelvic adhesion,the area under the curve(AUC)of FIB was 0.630,and the cut-off value was 2.87 g/L.The incidence of adhesions in patients with FIB greater than 2.87 g/L increased(χ2=15.4,P<0.01).CONCLUSION: Coagulation parameters was correlated with the pelvic adhesions in endometriosis,especially fibrinogen,which may help to judge the severity of pelvic adhesions caused by endometriosis.
