Clinical research of iron protein succinate on treatment of pregnant iron deficiency anemia
- Author:
Rong ZHOU
1
;
Lan XU
;
Yu-yan MA
;
Da-jun FANG
;
Lin-dong YANG
Author Information
- Publication Type:Journal Article
- Keywords: proteinironsuccinateoralsolution; irondeficiencyanemiaduringpregnancy; effectiveness; safety
- From: Chinese Journal of Practical Gynecology and Obstetrics 2019;35(03):343-346
- CountryChina
- Language:Chinese
- Abstract: OBJECTIVE:To evaluate the efficacy and safety of proteinsuccinic iron oral liquid on treatment of irondeficiency anemia in pregnant women by using polysaccharide iron complex as a control drug.METHODS:A total of 28724-28 weeks pregnant women that were diagnosed of IDA were randomly selected from six qualified Grade Ⅲ Ahospitals in Sichuan Province,Shaanxi Province,Guangdong Province,Shandong Province,and Jiangsu Province in2016. 144 cases were randomly Assigned in the control group and 143 cases in the test group. After 2 weeks and 4 weeksof treatment,various efficacy and safety indicators were detected and recorded.RESULTS:The improvement rate ofhemoglobin at 2 weeks and 4 weeks after treatment in the study group were 31.43% and 15.89%,respectively,which werehigher than 7.19% and 3.05% of the control group(P<0.05). The hemoglobin levels of the study group were also higherthan the polysaccharide iron complex at 2 and 4 weeks after treatment(P<0.05). There was no significant differencebetween the two groups in the improvement of serum ferritin and transferrin saturation(P>0.05). There was no significantdifference in the incidence of adverse reactions between the two groups(P>0.05).CONCLUSION:Protein iron succinateoral solution has less adverse reactions,easy absorption,good taste,and has a good therapeutic effect on pregnant irondeficiency anemia.
