Recognition of neurogenic myocardial injury

Author: Han CHEN ¹ ; Rong-guo YU ¹
Author Information

1. Provincial Clinical College of Fujian Medical University,Critical Care Center of Fujian Province,the Third Department of Critical Care Medicine,Fujian Provincial Hospital Fuzhou 350001,China
Publication Type:Journal Article
Keywords: neurogenic myocardium injury; brain injury; stress cardiomyopathy; catecholamine; troponin
From: Chinese Journal of Practical Internal Medicine 2019;39(12):1036-1039
CountryChina
Language:Chinese
Abstract: Transient,reversible myocardium injury can occur in patients with brain injury.Several pathophysiological mechanisms are involved in the development of such neurogenic myocardium injury.Excess catecholamine release plays a major role during myocardial injury.The clinical features include abnormal electrocardiographic,echocardiographic features and elevated biomarkers.In some patients stunned myocardium can be observed which may lead to hemodynamic instability or even cardiogenic shock.Inotropic agents and mechanical support are useful in improving cardiac function.β-adrenergic blockade is likely to attenuate the catecholamine toxicity but its use remains controversial.