Prognostic factors of esophageal cancer with multiple organ metastases and a prediction nomogram
- Author:
Zi-fan ZHANG
1
;
Zhi-yuan CHENG
1
;
Qian-qian MENG
;
Tian-jiao WANG
;
Han LIN
;
Lei XIN
;
Ling ZHANG
;
Luo-wei WANG
;
Zhao-shen LI
Author Information
- Publication Type:Journal Article
- Keywords: esophageal cancer; neoplasm metastasis; SEER database; prognosis analysis; nomogram
- From: Chinese Journal of Practical Internal Medicine 2019;39(07):607-612
- CountryChina
- Language:Chinese
- Abstract: OBJECTIVE: To investigate the prognostic factors of esophageal cancer with multiple organ metastases and establish a prognostic prediction model. METHODS: Patients data were extracted from the SEER database. The clinical data of 388 patients with esophageal cancer with multiple organ metastases were retrospectively analyzed. Risk factors were analyzed by log-rank method and survival curves were drawn by K-M method. Multivariate analysis was performed by Cox proportional hazard model to obtain independent prognostic factors for multi-organ metastasis of esophageal cancer. A prediction nomogram was further established.RESULTS: The mean survival time of patients in this study was 7.3 months, and the survival rates for 1-, 3-, and 5-year were 15.5%,1.2%, and 0, respectively. Age was an independent prognostic factor. The value of C-index was 0.618. CONCLUSION: The prognosis of esophageal cancer with multiple organ metastases is poor. Age at the diagnosis and patterns of multiple organ metastases are related to the survival time of patients. The prediction nomogram provided a good prognosis prediction.
