Severe Fever with Thrombocytopenia Syndrome Accompanied by Hemophagocytic Lymphohistiocytosis.
10.3904/kjm.2016.91.3.325
- Author:
Hyeong Jin KIM
1
;
Lae Hyung KANG
;
Jin Ho JANG
;
June Hyun KIM
;
Kwang Uk BAE
;
Eun Jung KIM
;
Su Jin LEE
Author Information
1. Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yansang, Korea. beauty192@hanmail.net
- Publication Type:Case Report
- Keywords:
Severe fever with thrombocytopenia syndrome;
Lymphohistiocytosis, Hemophagocytic;
Lymphoma
- MeSH:
Aged;
Biopsy;
Bone Marrow;
Bunyaviridae;
Emergency Service, Hospital;
Farmers;
Female;
Fever*;
Humans;
Leukopenia;
Liver;
Lymphohistiocytosis, Hemophagocytic*;
Lymphoma;
Polymerase Chain Reaction;
Thrombocytopenia*;
Ticks
- From:Korean Journal of Medicine
2016;91(3):325-329
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging disease caused by the SFTS virus (family Bunyaviridae, genus Phlebovirus). A 77-year-old female farmer was bitten by a tick and developed a fever 5 days later, resulting in admittance to the emergency room. The laboratory findings showed elevated liver enzyme levels, thrombocytopenia, and leukopenia. Lymphoma was suspected based on computed tomography results. After confirming SFTS virus infection via the polymerase chain reaction, a bone marrow biopsy revealed hemophagocytic lymphohistiocytosis (HLH). HLH is rarely observed in patients with SFTS and few studies have reported the presence of SFTS in bone marrow. Here, we report a case of SFTS that was initially mistaken for a lymphoma, and was accompanied by HLH.
