Two new monoterpenoids of <italic>Zingiber officinale</italic> peel

Yan GUO; Yan-zhi WANG; Zhi-pin XU; Man-qian LI; Xiao-juan ZHANG; Yu-fei LIU; Xue-yu HU; Wei-sheng FENG

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Two new monoterpenoids of Zingiber officinale peel

VernacularTitle:姜皮中两个新的单萜类化合物
Author: Yan GUO ¹ ; Yan-zhi WANG ^{1
,

2
,

3} ; Zhi-pin XU ¹ ; Man-qian LI ¹ ; Xiao-juan ZHANG ¹ ; Yu-fei LIU ¹ ; Xue-yu HU ¹ ; Wei-sheng FENG ^{1
,

2
,

3}
Author Information

1. School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China
2. Co-construction Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases by Henan &
3. Education Ministry of P. R. China, Zhengzhou 450046, China
Publication Type:Research Article
Keywords: Zingiberaceae; italic>Zingiber officinale peel; terpenoid; structural identification
From: Acta Pharmaceutica Sinica 2020;55(3):484-488
CountryChina
Language:Chinese
Abstract: The chemical constituents of Zingiber officinale peel were isolated and purified by various chromatographic separation techniques such as Diaion HP-20, MCI Gel CHP-20, Sephadex LH-20, ODS, silica gel and semi-preparative HPLC. Seven terpenoids were identified by physicochemical properties and spectral data: (4R,6S)-1-(hydroxymethyl)-5,5-dimethylbicyclo[3.1.1]hept-2-en-4-ol (1), 4-(hydroxymethyl)-1-isopropylcyclohex-2-ene-3,4-diol (2), 3,5,6-trihydroxy-7-megastigmen-9-one (3), 3-(3-hydroxybutyl)-2,4,4-trimethyl-2,5-cyclohexadien-1-one (4), angelicoidenol (5), grasshopper ketone (6), and dihydrophaseic acid (7), in which compounds 1, 2 are new compounds, named: (4R,6S)-1-(hydroxymethyl)-5,5-dimethylbicyclo[3.1.1]hept-2-en-4-ol and 4-(hydroxymethyl)-1-isopropylcyclohex-2-ene-3,4-diol, and compounds 3-7 were obtained from this plant for the first time.